The title for the new Indiana Jones movie has been revealed. More info about the Crystal Skull itself can be found in the above clip from Arthur C Clarke Mysterious World episode.
As is traditionally the case with Indiana Jones, the MacGuffin is the artifact. What the Crystal Skull is reportedly said to be able to do could be an indication of the movie's plot:
The Maya people said it was used to will death or to heal. And if like an older medicine man or witchdoctor was getting too old to perform a ceremony a young man was chosen and both laid in front of the alter and the high priest would perform a ceremony and the old man's knowledge would go into this young boy and the old man would pass away peacefully and this young boy would get up as a very knowledgeable young man. This crystal skull has tremendous power, but it also gives you a warning that something's going to happen.
Which is all pretty interesting stuff. Could Labeouf be the young man? And could John Hurt, allegedly playing Indy's mentor, Abner Ravenwood, be the old man and via this method passes on his knowledge to young Labeouf? Face it, John Hurt dies in practically every movie he's been in.